Cagrilintide (10 x vials)

Cagrilintide is a long-acting amylin analogue developed for weight management and type 2 diabetes treatment. Here are its primary uses:

Uses of Cagrilintide

1. Weight Management:

   • Obesity Treatment: Cagrilintide has shown significant efficacy in promoting weight loss in individuals with obesity. In clinical trials, participants treated with cagrilintide experienced dose-dependent weight loss, with higher doses leading to greater reductions in body weight. This makes it a promising option for long-term weight management​ (Med Xpress)​​ (Auctores)​.

2. Type 2 Diabetes Management:

   • Blood Glucose Control: When used in combination with semaglutide, another medication for diabetes, cagrilintide helps improve glycemic control. This combination has been shown to significantly lower HbA1c levels and improve other metabolic parameters in patients with type 2 diabetes​ (Auctores)​.

Mechanism of Action

Cagrilintide works by mimicking the effects of amylin, a hormone that helps regulate blood glucose levels and suppress appetite. It acts on both amylin and calcitonin receptors, which play a role in controlling food intake and body weight. By activating these receptors, cagrilintide helps reduce appetite and enhance feelings of fullness, leading to decreased food intake and subsequent weight loss​ (Med Xpress)​​ (Auctores)​.

Clinical Trials

• Combination Therapy: The combination of cagrilintide and semaglutide (known as CagriSema) has been tested in clinical trials and has shown superior weight loss outcomes compared to either drug alone. This combination therapy is currently being explored further in phase 3 trials to confirm its efficacy and safety for broader use​ (Med Xpress)​​ (Auctores)​.